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-why we found vitamin B6 (pyridoxine Hcl) in
components of some effervescent which indicated for
hyper oxalurea ? |
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Answer :
- the role of vit.B6 is to cut the mechanism of the
formation of endogenous hyper oxalurea.
-endogenous oxalate which produced from metabolic
process make complex with calcium ions &form
Ca.Oxalate crystals .
-vit.B6 catalyze the pyridoxal enzyme which
responsible for conversion of endogenous
oxalate to glyoxalate (protein form).
&so no endogenous Ca.oxalate crystals will be
formed.
-Note : vit.B6 found in*Citrocid Mg plus
effervescent .
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-Although *Cidophage (Metformin) is an anti-diabetic
drug but it used for treatment of (PCOs )
also……HOW??? |
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-Answer :
-PCOs(poly cystic ovarian syndrome )or hyper chronic
an ovulation is an endocrine disorder found in 5-10%
of women.
-it is a syndrome consist of amenorrhea ,hirsutism,
obesity &enlarged poly cystic ovaries.
-in the past it was thougt that(PCOs) was caused
buyexcess androgen production, but recent research
has shown that the hidden factor which causes the
problem is Insulin Resistance
which result in Hyper insulinemia over production of
testosterone concomitant
with decrease in sex hormone binding globulin(SHBG)
result in (PCOS) .
NOTE :
1)dose of metformin for (PCOs) :
1st weak :500mg/day
2nd weak :500mg twice daily.
Then :850mg twice daily or 1500mg/day (taken with
meals )
2)Metformin is a normoglycemic drug as it lower
elevated blood sugar level in diabetics ,
when given to non-diabetic they only lower insulin
level in blood &blood sugar level will not changed…
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-vitamin B12 (cyanocobalamin ) containing drugs
especially injection form prescribed by different
doses…?? |
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-Answer :
-vit.B12 found in market in three foms one is short
acting &the other two is long acting .
1)short acting :
-cyanocobalamine which found in *Tri-B ampoule in
combination with vit.B6 &B1.
-Dose is ampoule day after day.
2)Long acting
a)Hydroxocobalamin . e.g *Depovit ampoule
- common dose :ampoule every 3 days.
b)cyanocobalamin-tannin . e.g *Betolvex ampoule
-common dose : ampoule/weak.
-Note that cyanocobalamin-tannin is longer than
Hydroxocobalamin .
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